NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the main toxic effect of anthracyclines?

Nephrotoxicity
Myelosuppression
Cardiotoxicity
Constipation

The correct answer is: Cardiotoxicity

Anthracyclines are known to have a variety of toxic effects on the body, but the most significant and well-documented one is cardiotoxicity. This means that these drugs can potentially cause damage to the heart, leading to serious complications such as heart failure. Nephrotoxicity, myelosuppression, and constipation are also known adverse effects of anthracyclines, but they are not considered the primary or most serious toxic effect of this class of drugs.