NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the maximum daily dose of Bupropion due to the risk of seizures?

  1. 300 mg/day

  2. 400 mg/day

  3. 450 mg/day

  4. 500 mg/day

The correct answer is: 450 mg/day

Bupropion is an antidepressant medication that is known to lower the seizure threshold. Therefore, it is essential to be cautious with the dosing to minimize the risk of seizures. The maximum recommended daily dose of Bupropion for this reason is 450 mg/day. Exceeding this dose can significantly increase the likelihood of seizures in patients. Option A (300 mg/day), Option B (400 mg/day), and Option D (500 mg/day) are incorrect as they fall below or exceed the advised maximum daily dose of Bupropion.