NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the maximum dose of Lovastatin when taken with Non-DHP CCBs?

  1. 40 mg

  2. 20 mg

  3. 10 mg

  4. 5 mg

The correct answer is: 20 mg

Non-DHP CCBs are known to increase the exposure of Lovastatin in the body, leading to a higher risk of side effects such as myopathy and rhabdomyolysis. Therefore, a lower dose of Lovastatin is recommended when taken with Non-DHP CCBs in order to minimize this risk. Option A, 40 mg, is too high and can increase the likelihood of side effects. Option C, 10 mg, may still be too high for some individuals and should be adjusted based on individual risk factors. Option D, 5 mg, is too low and may not be effective in lowering cholesterol levels. Therefore, option B, 20 mg, is the recommended maximum dose of Lovastatin when taken with Non-DHP CCBs.

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