NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the maximum lifetime dose recommendation for Bleomycin due to the risk of pulmonary fibrosis?

  1. 200 units

  2. 300 units

  3. 400 units

  4. 500 units

The correct answer is: 400 units

Bleomycin is an anticancer medication known for its potential to cause pulmonary fibrosis, a serious and potentially fatal side effect. Due to this risk, there is a maximum lifetime cumulative dose recommendation to minimize the risk of developing pulmonary fibrosis. The maximum lifetime dose recommendation for Bleomycin is 400 units. Exceeding this dose limit significantly increases the risk of pulmonary toxicity. Therefore, it is crucial for healthcare providers to closely monitor the cumulative dose of Bleomycin administered to patients to prevent this severe adverse effect.

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