NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the mechanism of action for Omalizumab?

  1. Blocks leukotriene receptors

  2. Inhibits IgE binding on mast cells and basophils

  3. Blocks cytokine release from T-cells

  4. Inhibits phosphodiesterase

The correct answer is: Inhibits IgE binding on mast cells and basophils

Omalizumab is a monoclonal antibody that works by inhibiting IgE binding on mast cells and basophils. This mechanism of action reduces the release of inflammatory mediators triggered by IgE, leading to a decrease in allergic responses. Therefore, option B is the correct answer. The other options (A, C, D) are incorrect as they do not accurately describe the mechanism of action of Omalizumab.

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