NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the mode of action for the hyperhidrosis treatment glycopyrronium?

Anticholinergic
Antiperspirant
Steroid
Immunosuppressant

The correct answer is: Anticholinergic

Glycopyrronium's mode of action for treating hyperhidrosis is as an anticholinergic agent. Anticholinergics work by blocking the action of acetylcholine, a neurotransmitter that stimulates sweat glands. By inhibiting this stimulation, anticholinergics like glycopyrronium help reduce excessive sweating. The other options, antiperspirant, steroid, and immunosuppressant, are not correct in the context of glycopyrronium's mode of action for hyperhidrosis. Antiperspirants work by blocking sweat ducts, steroids have anti-inflammatory effects, and immunosuppressants decrease the activity of the immune system - none of which are mechanisms of action for glycopyrronium in treating hyperhidrosis.