NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the primary concern using Long-acting Beta-2 Agonists (LABA) in asthma therapy?

  1. Increased risk of pneumonia

  2. Oral candidiasis

  3. Increased risk of death/hospitalizations if used as monotherapy

  4. Increased risk of osteoporosis

The correct answer is: Increased risk of death/hospitalizations if used as monotherapy

The primary concern with using Long-acting Beta-2 Agonists (LABA) in asthma therapy is the increased risk of death or hospitalizations if used as monotherapy. LABAs should never be used as monotherapy for asthma due to the potential for serious adverse events such as worsening of asthma symptoms and increased risk of severe exacerbations. It is essential to always use LABAs in combination with inhaled corticosteroids to provide effective asthma control and reduce the risk of adverse outcomes. Options A, B, and D are not the primary concerns associated with using LABAs in asthma therapy.

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