NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the recommended management for Myelosuppression-induced Neutropenia?

  1. Antibiotics

  2. Colony-stimulating factors

  3. RBC transfusions

  4. Platelet transfusions

The correct answer is: Colony-stimulating factors

Myelosuppression-induced neutropenia refers to a condition where there is a decrease in white blood cells, particularly neutrophils, due to suppression of the bone marrow. The recommended management for this condition is the use of colony-stimulating factors. Colony-stimulating factors such as granulocyte colony-stimulating factor (G-CSF) or granulocyte-macrophage colony-stimulating factor (GM-CSF) can help stimulate the production of white blood cells, specifically neutrophils, to combat the neutropenia. This treatment option aims to increase the neutrophil count and reduce the risk of infection in affected individuals. Antibiotics (Choice A) may be used in the presence of an infection but are not the primary recommended management for neutropenia itself. RBC transfusions (Choice C) and platelet transfusions (Choice D) are not indicated for managing myelosuppression-induced neutropenia.