NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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What is the treatment of choice for severe SSTIs in hospital settings?

Ceftaroline
Amoxicillin
Mupirocin
Macrodantin

The correct answer is: Ceftaroline

Ceftaroline is the correct answer for the treatment of choice for severe SSTIs in hospital settings due to its broad spectrum of activity against Gram-positive bacteria including MRSA. Ceftaroline is a fifth-generation cephalosporin with activity against methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae. It is particularly effective in treating complicated skin and soft tissue infections where MRSA is a concern. Amoxicillin and Macrodantin are not typically the treatment of choice for severe SSTIs in a hospital setting due to limited antimicrobial spectrum and efficacy. Mupirocin is an antibacterial used for the treatment of impetigo and nasal decolonization of MRSA; it is not typically used as the primary treatment for severe SSTIs in a hospital setting.