NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What kind of drugs can increase intra-ocular pressure (IOP)?

  1. Antibiotics

  2. Antivirals

  3. Anticholinergics

  4. Analgesics

The correct answer is: Anticholinergics

Drugs that increase intra-ocular pressure (IOP) are known as glaucoma-inducing drugs. This is because they can increase the pressure inside the eye, damaging the optic nerve and leading to vision loss. Antibiotics and antivirals do not typically have any effect on IOP, while analgesics (pain relievers) can actually decrease IOP. Anticholinergics, on the other hand, work by blocking the action of the neurotransmitter acetylcholine, which can result in an increase in IOP. Therefore, anticholinergics are the only correct answer as they can potentially cause harm to the eyes by increasing IOP.

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