NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What major side effect is associated with Hydroxychloroquine?

  1. Hepatotoxicity

  2. Myelosuppression

  3. Irreversible retinopathy

  4. Teratogenicity

The correct answer is: Irreversible retinopathy

Hydroxychloroquine has been known to cause irreversible retinopathy, a serious side effect that affects the eyes and can potentially lead to vision loss. While there is a possibility of Hepatotoxicity (liver damage) and Myelosuppression (decrease in blood cell production) with Hydroxychloroquine use, these are not the major side effects associated with this medication. Additionally, Hydroxychloroquine has been found to be potentially teratogenic (harmful to a developing fetus) if taken during pregnancy, but this is not the major side effect that is most closely associated with this medication. Therefore, C Irreversible retinopathy is the most accurate answer.

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