What off-label use is mentioned for SIADH treatment?

Demeclocycline is the correct off-label use mentioned for the treatment of Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Demeclocycline is a tetracycline antibiotic that has the unique property of inducing nephrogenic diabetes insipidus, which can help counteract the excessive antidiuretic hormone activity seen in SIADH. This medication is used off-label specifically for this purpose.

Ibuprofen, acetaminophen, and penicillin are not typically used for the treatment of SIADH. Ibuprofen and acetaminophen are nonsteroidal anti-inflammatory drugs (NSAIDs) used mainly for pain relief and reducing inflammation, while penicillin is an antibiotic used to treat bacterial infections.