NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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What off-label use is mentioned for SIADH treatment?

  1. Democlocycline

  2. Ibuprofen

  3. Acetaminophen

  4. Penicillin

The correct answer is: Democlocycline

Demeclocycline is the correct off-label use mentioned for the treatment of Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Demeclocycline is a tetracycline antibiotic that has the unique property of inducing nephrogenic diabetes insipidus, which can help counteract the excessive antidiuretic hormone activity seen in SIADH. This medication is used off-label specifically for this purpose. Ibuprofen, acetaminophen, and penicillin are not typically used for the treatment of SIADH. Ibuprofen and acetaminophen are nonsteroidal anti-inflammatory drugs (NSAIDs) used mainly for pain relief and reducing inflammation, while penicillin is an antibiotic used to treat bacterial infections.