NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What should be stopped 4 weeks after travel for malaria prophylaxis?

  1. Doxycycline (Doryx, vibramycin)

  2. Atovaquone/proguanil (malarone)

  3. Primaquine

  4. Mefloquine

The correct answer is: Doxycycline (Doryx, vibramycin)

For malaria prophylaxis, Doxycycline should be stopped 4 weeks after travel. This is because Doxycycline is usually taken once daily starting 1 to 2 days before entering a malaria-endemic area, then continued daily during the stay, and for 4 weeks after leaving the area. As for the other options: - Atovaquone/proguanil is typically taken daily starting 1-2 days prior to travel, during the stay, and then for 7 days after leaving the area. - Primaquine is not typically used as a first-line agent for malaria prophylaxis. - Mefloquine is usually taken once weekly starting 1-2 weeks before travel, during the stay, and then for 4 weeks after leaving the area.

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