NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Disable ads (and more) with a membership for a one time $2.99 payment

Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

Practice this question and more.

What side effect is associated with Tygecycline when used in patients taking warfarin?

Decrease in INR
Increase in INR
No effect on INR
Decrease in blood pressure

The correct answer is: Increase in INR

When Tygecycline is used in patients taking warfarin, it can lead to an increase in the International Normalized Ratio (INR). Tygecycline can inhibit the metabolism of warfarin, leading to higher levels of warfarin in the blood and subsequently increasing the INR. This interaction can potentially result in an increased risk of bleeding for the patient. Therefore, monitoring the INR closely and adjusting warfarin doses accordingly is crucial in these situations. Option A is incorrect because the expected effect when using Tygecycline in patients taking warfarin is an increase in the INR, not a decrease. Option C is incorrect as there is an established interaction between Tygecycline and warfarin that can impact the INR. Option D is incorrect as the side effect associated with Tygecycline in patients taking warfarin is primarily related to the INR levels and not a decrease in blood pressure.