NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What signifies immunocompromised states relevant to the usage of certain medications?

CD4+ < 200 cells/mm3
Virulence of opportunistic infections
Existence of opportunistic infections
Daily use of antiretroviral therapy

The correct answer is: CD4+ < 200 cells/mm3

Immunocompromised states are conditions in which the immune system is weakened and less able to fight off infections and diseases. A CD4+ count of less than 200 cells/mm3 is a critical indicator of an immunocompromised state as it signifies a significant depletion of important immune cells. The other options, while relevant to immunocompromised states and the usage of certain medications, do not specifically signify an immunocompromised state. Option B and C refer to the presence and virulence of opportunistic infections, which can be a result of immunocompromised states but do not necessarily signify it. Option D, daily use of antiretroviral therapy, may be a treatment for an immunocompromised state but not a direct indicator of it.