NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What type of toxicity is Cisplatin most known for?

  1. Cardiotoxicity

  2. Pulmonary toxicity

  3. Nephrotoxicity

  4. Hepatotoxicity

The correct answer is: Nephrotoxicity

Cisplatin is most commonly known for causing nephrotoxicity, or harm to the kidneys. This is because cisplatin is mainly excreted through the kidneys, which can lead to damage if high levels of the drug are present. While Cisplatin can also cause side effects such as nausea and hair loss, it is most notable for its nephrotoxicity. Cardiotoxicity, pulmonary toxicity, and hepatotoxicity are not typically associated with Cisplatin use. Therefore, options A, B, and D are incorrect. The correct answer for the type of toxicity most commonly associated with Cisplatin is C Nephrotoxicity.

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