NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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When adjusting basal insulin for T1D, what indicates a need to decrease the dose?

  1. Low BG trend

  2. High BG trend

  3. Stable BG levels

  4. After meals

The correct answer is: Low BG trend

When adjusting basal insulin for Type 1 Diabetes (T1D), a low blood glucose (BG) trend indicates a need to decrease the dose. This is because consistently low BG levels indicate that the current basal insulin dose may be too high, leading to hypoglycemia. Therefore, if a patient with T1D is experiencing a trend of low BG levels, it is important to decrease the basal insulin dose to prevent further hypoglycemia episodes. In contrast: - High BG trend (option B) would typically indicate a need to increase the basal insulin dose to better control blood glucose levels. - Stable BG levels (option C) suggest that the current basal insulin dose is appropriate and may not require any adjustments. - After meals (option D) refers to postprandial glucose levels, which are influenced by prandial insulin doses rather than basal insulin. Adjustments in basal insulin are generally made based on fasting or pre-meal BG levels.