NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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When should the first dose of colony stimulating factors be administered relative to chemotherapy?

  1. Immediately after chemo

  2. No sooner than 24 hours after chemo

  3. At least 12 days before the next chemo cycle

  4. Within 7 days after chemo

The correct answer is: No sooner than 24 hours after chemo

Colony stimulating factors, which stimulate the production of white blood cells in the body, should be given after chemotherapy in order to reduce the risk of infection. Option A is incorrect because giving them immediately after chemo can increase the side effects. Option C is incorrect because it is too early and may not have a significant enough effect. Option D is incorrect because it is recommended to give colony stimulating factors within 24 hours after chemo, not within 7 days. Therefore, option B - no sooner than 24 hours after chemo - is the most appropriate time to administer the first dose of colony stimulating factors.

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