NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Disable ads (and more) with a membership for a one time $4.99 payment

Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

Start Multiple Choice Practice Test
Start Flash Cards

Practice this question and more.

Where do SGLT2 inhibitors work in the kidney?

  1. Proximal tubule

  2. Loop of Henle

  3. Distal convoluted tubule

  4. Collecting duct

The correct answer is: Proximal tubule

SGLT2 inhibitors primarily work in the proximal tubule of the kidney. This is where the majority of glucose reabsorption occurs. The other options, such as the loop of Henle, distal convoluted tubule, and collecting duct, do not play a significant role in glucose reabsorption. The loop of Henle is responsible for reabsorbing water and sodium, while the distal convoluted tubule is responsible for potassium and sodium reabsorption. The collecting duct mainly regulates water reabsorption. Therefore, these options are not directly involved in the mechanism of action of SGLT2 inhibitors.

More Questions Like This