NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which agent is not recommended to combine with Isotretinoin during acne treatment?

  1. Steroids

  2. Progestin-only birth control

  3. Vitamin A supplements

  4. Calcium supplements

The correct answer is: Calcium supplements

Calcium supplements are not recommended to be combined with Isotretinoin during acne treatment. Isotretinoin itself is derived from vitamin A and can lead to increased levels of calcium in the blood, which might result in potential risks such as hypercalcemia. Therefore, combining Isotretinoin with calcium supplements may exacerbate this risk. On the other hand, steroids, progestin-only birth control, and vitamin A supplements are often used in combination with Isotretinoin for acne treatment without posing significant risks.

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