NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which antibiotic does not require renal dose adjustments?

Moxifloxacin
Aminoglycosides
Cefepime
Pip/tazo

The correct answer is: Moxifloxacin

Moxifloxacin is the only antibiotic in this list that does not require renal dose adjustments. Aminoglycosides and Cefepime are both known to have potential nephrotoxicity and require adjustments in patients with renal impairment. Pip/tazo is also known to have nephrotoxic effects and requires dose adjustments in patients with renal insufficiency. Moxifloxacin, on the other hand, is metabolized primarily by the liver and does not require dose adjustments in patients with renal impairment.