NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which antibiotic has activity against most gram-positive bacteria including CA-MRSA and anaerobes?

  1. Lefamulin

  2. Metronidazole

  3. Rifaximin

  4. Clindamycin

The correct answer is: Clindamycin

Clindamycin is the correct answer because it is a broad-spectrum antibiotic that has activity against most gram-positive bacteria, including CA-MRSA (community-acquired methicillin-resistant Staphylococcus aureus) and anaerobes. This means that it can effectively target and kill the majority of these types of bacteria. Lefamulin may have some activity against gram-positive bacteria, but it is primarily used to treat community-acquired pneumonia caused by certain strains of Streptococcus pneumoniae. Metronidazole is primarily used to treat anaerobic infections and is not as effective against gram-positive bacteria. Rifaximin is primarily used to treat traveler's diarrhea and certain types of abdominal infections, and is not effective against gram-positive bacteria, including CA-MRSA. Therefore, these options are incorrect in relation to the question.