NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which antibiotic should not be used for pneumonia in nosocomial MRSA infections?

Daptomycin
Vancomycin
Linezolid
Ceftaroline

The correct answer is: Daptomycin

For pneumonia in nosocomial MRSA infections, Daptomycin should not be used because it is inactivated by pulmonary surfactant. This decreases its efficacy in treating pulmonary infections, making it not ideal for this specific scenario. Vancomycin, Linezolid, and Ceftaroline are all appropriate choices for treating pneumonia in nosocomial MRSA infections. Vancomycin and Linezolid are commonly used to treat MRSA infections, including pneumonia, while Ceftaroline is a newer cephalosporin with activity against MRSA.