NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which antibiotics cover MSSA only and do not require renal dose adjustment?

  1. Penicillin VK

  2. Amoxicillin

  3. Dicloxacillin, nafcillin, oxacillin

  4. Amoxicillin/Clavulanate

The correct answer is: Dicloxacillin, nafcillin, oxacillin

Explanation Dicloxacillin, nafcillin, and oxacillin are specifically designed to cover MSSA bacteria and do not require renal dose adjustment. Option A, Penicillin VK, does not cover MSSA and thus is not the correct answer. Option B, Amoxicillin, does not require renal dose adjustment but does not specifically target MSSA bacteria. Option D, Amoxicillin/Clavulanate, does not cover MSSA and also requires renal dose adjustment. Therefore, the most accurate answer is C.