NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which bacteria is not typically targeted in the empirical treatment of acute uncomplicated cystitis?

  1. Pseudomonas

  2. Proteus

  3. E. coli

  4. Klebsiella

The correct answer is: Pseudomonas

In the empirical treatment of acute uncomplicated cystitis, the first-line antibiotics target the most common causative agent, which is Escherichia coli (E. coli). Pseudomonas aeruginosa is not typically seen as a causative agent in uncomplicated cystitis. It is more commonly associated with complicated urinary tract infections, such as those related to catheter use or in patients with structural abnormalities of the urinary tract. Therefore, Pseudomonas is not typically targeted in the empirical treatment of acute uncomplicated cystitis, making it the correct answer. Proteus, E. coli, and Klebsiella are commonly targeted in the empirical treatment of acute uncomplicated cystitis due to their frequent involvement in these infections.

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