NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Disable ads (and more) with a membership for a one time $4.99 payment

Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

Start Multiple Choice Practice Test
Start Flash Cards

Practice this question and more.

Which compound is mentioned as a CYP-3A4 inhibitor?

  1. St. John's wort

  2. Grapefruit juice

  3. R-warfarin

  4. Apixaban

The correct answer is: Grapefruit juice

Grapefruit juice is mentioned as a CYP-3A4 inhibitor as it can increase the activity of this enzyme, leading to decreased metabolism of certain medications, including those listed in options C and D. Option A, St. John's wort, is known to induce CYP-3A4, which would have the opposite effect. Therefore, this compound is not mentioned as a CYP-3A4 inhibitor. While option D, Apixaban, is metabolized by CYP-3A4, it is not specifically mentioned as a CYP-3A4 inhibitor.

More Questions Like This