NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which drug increases liver function tests (LFTs) listed under gout treatment?

  1. Allopurinol

  2. Febuxostat

  3. Colchicine

  4. Indomethacin

The correct answer is: Febuxostat

Febuxostat is the correct answer because it is associated with elevations in liver function tests (LFTs). Monitoring LFTs is recommended during treatment with Febuxostat due to the potential for liver toxicity. Allopurinol, Colchicine, and Indomethacin are commonly used in the treatment of gout but are not typically associated with significant elevations in LFTs.