NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which drug is associated with optic neuropathy?

  1. Amiodarone

  2. Ethambutol

  3. Chloroquine

  4. Digoxin

The correct answer is: Ethambutol

Ethambutol is a commonly used anti-tuberculosis medication that can cause optic neuropathy, a condition that affects the optic nerve and can potentially lead to vision loss. Amiodarone is a medication used to treat heart rhythm disorders and has been associated with several ocular side effects, but not optic neuropathy specifically. Chloroquine is an anti-malarial drug that has been linked to eye toxicity, but not optic neuropathy. Digoxin is a medication used to treat heart failure and has not been associated with causing optic neuropathy. Therefore, the correct answer is B because it is the only drug listed that is specifically associated with optic neuropathy.

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