NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which drug is known to have sorption or leaching issues with PVC?

  1. Lorazepam

  2. Paracetamol

  3. Ibuprofen

  4. Vitamin C

The correct answer is: Lorazepam

Lorazepam is the correct answer because it is known to have sorption or leaching issues with PVC (polyvinyl chloride) containers or tubing commonly used in intravenous administration sets. PVC can absorb certain medications, leading to reduced drug concentrations in the solution being administered. This interaction can decrease the effectiveness of the medication and potentially impact patient care. Therefore, it is important to be cautious when administering lorazepam or other medications that are prone to sorption or leaching issues with PVC materials. Regarding the other options: - Paracetamol, Ibuprofen, and Vitamin C do not have significant sorption or leaching issues with PVC materials.