NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which drug is used for continuous IV infusion in prostacyclin analogues treatment for PAH?

  1. Bosentan

  2. Epoprostenol (Flolan)

  3. Ambrisentan

  4. Macitentan

The correct answer is: Epoprostenol (Flolan)

Epoprostenol (Flolan) is the correct answer because it is used for continuous intravenous infusion in the treatment of pulmonary arterial hypertension (PAH) as a prostacyclin analogue. Prostacyclin analogues help to dilate blood vessels, prevent blood clotting, and improve symptoms in patients with PAH. Options A, C, and D (Bosentan, Ambrisentan, Macitentan) are incorrect because they are endothelin receptor antagonists used for the treatment of PAH but are not administered via continuous intravenous infusion like epoprostenol. These drugs work by blocking the effects of endothelin, a substance that narrows blood vessels and worsens PAH symptoms but are not prostacyclin analogues used for continuous IV infusion.