NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which drug requires a filter for administration?

  1. SMX/TMP

  2. Phenytoin (continuous infusions)

  3. Metronidazole

  4. Acetaminophen

The correct answer is: Phenytoin (continuous infusions)

Phenytoin requires a filter for administration because it is known to precipitate in IV solutions, which can lead to serious consequences if administered without proper filtration. Adding a filter helps trap any precipitates and prevent them from entering the patient's bloodstream, reducing the risk of complications such as clogged IV lines or vascular damage. This precaution is essential when administering phenytoin through continuous infusions to ensure patient safety. The other options, such as SMX/TMP, Metronidazole, and Acetaminophen, do not typically require a filter for administration.

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