NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which is not an inducer of CYP-1A2?

  1. St. John's wort

  2. Ritonavir

  3. Ciprofloxacin

  4. Smoking

The correct answer is: Ciprofloxacin

Ciprofloxacin is not an inducer of CYP-1A2. The correct answer is Ciprofloxacin because it is actually an inhibitor of CYP-1A2, not an inducer. St. John's wort, Ritonavir, and smoking are all known to induce CYP-1A2 activity, leading to the potential for drug interactions with medications that are metabolized by this enzyme.

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