NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which medication class can be combined with intranasal steroids for better efficacy?

  1. Decongestants

  2. Intranasal antihistamines

  3. First generation antihistamines

  4. Second generation oral antihistamines

The correct answer is: Intranasal antihistamines

Intranasal antihistamines can be combined with intranasal steroids for better efficacy. Decongestants may provide temporary relief, but they do not have the same anti-inflammatory effects as intranasal steroids. First generation antihistamines can also provide temporary relief, but they may cause drowsiness and have limited effectiveness in treating allergies. Second generation oral antihistamines may also be effective on their own, but when combined with intranasal steroids, there is a potential for excess dryness and irritation in the nose. Therefore, intranasal antihistamines are the best choice to combine with intranasal steroids for optimal allergy relief.

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