NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which medication class does rilpivirine belong to?

  1. NRTIs

  2. NNRTIs

  3. INSTIs

  4. PIs

The correct answer is: NNRTIs

Rilpivirine belongs to the class of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs). NNRTIs work by binding directly to the reverse transcriptase enzyme, blocking its function and preventing the virus from replicating. This class of medications is commonly used in the treatment of HIV infection. Choice A, NRTIs (Nucleoside Reverse Transcriptase Inhibitors), and Choice C, INSTIs (Integrase Strand Transfer Inhibitors), are both other classes of antiretroviral medications used in the treatment of HIV, but rilpivirine specifically belongs to the NNRTIs. Choice D, PIs (Protease Inhibitors), is another class of antiretroviral medications used in HIV treatment, but rilpivirine does not belong to this class.

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