NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which medication for CINV is associated with QT prolongation and serious arrhythmias?

  1. Metoclopramide

  2. Droperidol

  3. Olanzapine

  4. Prochlorperazine

The correct answer is: Droperidol

Answer Droperidol is associated with QT prolongation and serious arrhythmias due to its potential to block potassium ion channels in the heart, leading to an abnormal heart rhythm. Metoclopramide, Olanzapine, and Prochlorperazine are not associated with QT prolongation. Although they may have other side effects, they are not known to cause serious arrhythmias. Therefore, B is the most appropriate answer.

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