NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Disable ads (and more) with a membership for a one time $4.99 payment

Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

Practice this question and more.


Which medication is an IL-1 receptor antagonist?

  1. Rituximab

  2. Anakinra

  3. Abatacept

  4. Tocilizumab

The correct answer is: Anakinra

Anakinra is the correct answer because it is an IL-1 receptor antagonist. Anakinra works by competitively inhibiting the binding of interleukin-1 (IL-1) to the interleukin-1 receptor. This action helps to reduce inflammation and is used in conditions such as rheumatoid arthritis and other inflammatory disorders. The other options listed are not IL-1 receptor antagonists. Rituximab is a monoclonal antibody that targets CD20 on B cells. Abatacept is a selective T-cell costimulation modulator that inhibits T cell activation by binding to CD80 and CD86 on antigen-presenting cells. Tocilizumab is a monoclonal antibody that targets the interleukin-6 (IL-6) receptor, not the IL-1 receptor.