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Which medication is associated with cardiotoxicity?
Trastuzumab
Everolimus
Carfilzomib
Brentuximab
The correct answer is: Trastuzumab
Trastuzumab is associated with cardiotoxicity because it can lead to left ventricular dysfunction and heart failure. This medication's cardiotoxic effects can be severe and potentially life-threatening. Monitoring for cardiac function is crucial during treatment with trastuzumab to detect any signs of cardiotoxicity early and take appropriate management steps. Everolimus, Carfilzomib, and Brentuximab are not typically associated with cardiotoxicity. Everolimus is an mTOR inhibitor used in various types of cancer, Carfilzomib is a proteasome inhibitor mainly indicated for multiple myeloma, and Brentuximab is an antibody-drug conjugate utilized in Hodgkin lymphoma and systemic anaplastic large cell lymphoma. Although these medications can have other side effects, cardiotoxicity is not a commonly reported issue with their use.