NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which medication is contraindicated in CKD patients with a GFR<30?

Metformin
Levothyroxine
Aspirin
Lisinopril

The correct answer is: Metformin

Metformin is contraindicated in chronic kidney disease (CKD) patients with a glomerular filtration rate (GFR) less than 30 because it can increase the risk of lactic acidosis. Lactic acidosis is a serious and potentially life-threatening medical condition that can occur when too much lactic acid builds up in the body. The other options are incorrect because they do not specifically have a contraindication for CKD patients with a GFR<30. However, it is important for CKD patients to discuss all medications, including levothyroxine, aspirin, and lisinopril, with their healthcare provider and follow their recommendations.