NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which medication is contraindicated with strong CYP3A4 inducers?

  1. Viekira Pak

  2. Tenofovir

  3. Entecavir

  4. Interferon alpha

The correct answer is: Viekira Pak

Viekira Pak is a medication used to treat hepatitis C. Strong CYP3A4 inducers are substances that increase the activity of a specific enzyme in the liver, which can lead to faster breakdown of medications and decrease their effectiveness. Viekira Pak is specifically contraindicated with strong CYP3A4 inducers because it may not work as intended and could potentially lead to treatment failure. The other options, Tenofovir, Entecavir, and Interferon alpha, are medications used to treat different conditions and are not known to be contraindicated with strong CYP3A4 inducers.