NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which medication is specifically used ONLY for the prevention of acute rejection in transplant patients?

  1. Mycophenolate mofetil

  2. Tacrolimus

  3. Basiliximab

  4. Antithymocyte globulin

The correct answer is: Basiliximab

Basiliximab is the correct answer because it is a monoclonal antibody that specifically targets and inhibits interleukin-2 receptors on activated T-lymphocytes. By inhibiting this pathway, basiliximab helps to prevent acute rejection in transplant patients by suppressing the immune response directed at the transplanted organ. The other options listed, such as mycophenolate mofetil, tacrolimus, and antithymocyte globulin, are also used in transplant patients, but they have broader mechanisms of action beyond just the prevention of acute rejection.

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