NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which medication is the safest in heart failure among the Dihydropyridine CCBs?

Nicardipine
Amlodipine
Nifedipine
Clevidipine

The correct answer is: Amlodipine

Dihydropyridine calcium channel blockers (CCBs) are commonly used for the treatment of high blood pressure and heart failure. These medications work by relaxing and widening blood vessels, which helps to lower blood pressure and improve heart function. Among the Dihydropyridine CCBs, Amlodipine is considered the safest medication for heart failure. This is because it has a longer duration of action compared to other Dihydropyridine CCBs, meaning it stays in the body for a longer period of time and provides a more consistent effect. Additionally, Amlodipine has been shown to have a lower risk of adverse effects such as worsening heart failure or causing low blood pressure. Therefore, Amlodipine is the preferred option for patients with heart failure among the Dihydropyridine CCBs. The other options, including Nicardipine, Nifedipine, and Clevidipine, are also Dihydropyridine CCBs but have a shorter duration of action and may pose a higher risk of adverse effects in patients with heart failure.