NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which medication mentioned has a Black Box Warning for initiating in a hospital due to the risk of ODS?

Conivaptan
Tolvaptan
Mirabegron
Desmopressin

The correct answer is: Tolvaptan

Tolvaptan has a Black Box Warning for initiating in a hospital due to the risk of overly rapid correction of hyponatremia and the associated risk of osmotic demyelination syndrome (ODS). ODS is a severe neurologic condition that can occur when sodium levels are corrected too quickly, leading to damage of the myelin sheaths that protect nerve cells in the brain. Conivaptan, Mirabegron, and Desmopressin do not have Black Box Warnings for initiating in a hospital due to the risk of ODS.