NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which medication requires premedication with steroid, APAP, and antihistamine?

Rituxan
Kineret
Orencia
Simponi

The correct answer is: Rituxan

Rituxan is the correct answer because it is a monoclonal antibody used for the treatment of various conditions such as rheumatoid arthritis, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia. Due to the risk of infusion reactions such as fever, chills, and allergic reactions, premedication with a steroid, acetaminophen (APAP), and an antihistamine is necessary to help mitigate these potential side effects and ensure a safe administration process. The other options, Kineret, Orencia, and Simponi, are biologic medications used to treat conditions like rheumatoid arthritis as well, but they do not typically require premedication with a steroid, APAP, and antihistamine like Rituxan does.