NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which medication requires premedication with diphenhydramine to prevent specific side effects?

Everolimus
Bevacizumab
Temsirolimus
Pembrolizumab

The correct answer is: Temsirolimus

Premedication with diphenhydramine is required for temsirolimus due to its potential side effects of infusion-related reactions, including chills, fever, and flushing. This medication is an mTOR inhibitor used for the treatment of advanced renal cell carcinoma. Everolimus (A) and bevacizumab (B) are also used for the treatment of cancer but do not require premedication with diphenhydramine. Pembrolizumab (D) is an immune checkpoint inhibitor used for the treatment of various cancers, but it does not have any known side effects that require diphenhydramine premedication.