NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which non-selective beta blocker is used for the prevention of variceal bleeding?

  1. Nadolol

  2. Lisinopril

  3. Atenolol

  4. Metoprolol

The correct answer is: Nadolol

Nadolol is the correct answer for the prevention of variceal bleeding. Nadolol is a non-selective beta blocker that has been shown to reduce the risk of bleeding from esophageal varices by lowering the portal pressure. It achieves this by reducing cardiac output and splanchnic blood flow, thus decreasing the pressure in the portal vein. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor used for managing hypertension and heart failure. It does not have the same effect on preventing variceal bleeding as nadolol. Atenolol and metoprolol are selective beta blockers and are not typically used for the prevention of variceal bleeding as non-selective beta blockers like nadolol are more effective for this specific indication.

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