NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which of the following drugs can cause Cardiomyopathy?

Carmustine
Arsenic trioxide
Anthracyclines
Bicalutamide

The correct answer is: Anthracyclines

Anthracyclines are known to cause cardiomyopathy. Anthracyclines such as doxorubicin are commonly used in chemotherapy regimens for various types of cancer. However, one of the significant side effects of anthracyclines is cardiotoxicity, which can lead to cardiomyopathy. This toxicity is dose-dependent and can be cumulative, causing damage to the heart muscles over time. Therefore, patients receiving anthracyclines need close monitoring of their cardiac function to detect and manage cardiomyopathy early. Carmustine (Choice A), Arsenic trioxide (Choice B), and Bicalutamide (Choice D) are not typically associated with causing cardiomyopathy. Carmustine is an alkylating agent used in chemotherapy for certain types of cancer; Arsenic trioxide is used in the treatment of acute promyelocytic leukemia; and Bicalutamide is an androgen receptor antagonist used in the treatment of prostate cancer. While these medications have their own set of potential side effects, they are not commonly linked to the development of cardiomyopathy like anthracyclines are.