NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which of the following is NOT used for CRE coverage?

  1. Ceftazidime/avibactam

  2. Colistimethate

  3. Metronidazole

  4. Polymixin B

The correct answer is: Metronidazole

CRE coverage stands for carbapenem-resistant Enterobacteriaceae coverage. This refers to antibiotics that are effective against bacteria that are resistant to the antibiotic carbapenem. Metronidazole is not used for CRE coverage because it is not effective against carbapenem-resistant bacteria. Ceftazidime/avibactam, colistimethate, and polymixin B are all antibiotics that can be used for CRE coverage as they are effective against carbapenem-resistant bacteria.