NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which of the following P2Y12 inhibitors requires a transition to oral form after PCI?

  1. Clopidogrel

  2. Prasugrel

  3. Ticagrelor

  4. Cangrelor

The correct answer is: Cangrelor

After a percutaneous coronary intervention (PCI), Cangrelor is used intravenously as an antiplatelet agent to prevent thrombotic complications. Unlike the other options listed, Cangrelor has a rapid onset of action and is reversible once discontinued, making it suitable for use in a hospital setting during PCI procedures. The other P2Y12 inhibitors mentioned (Clopidogrel, Prasugrel, and Ticagrelor) are taken orally and do not require a transition to an intravenous form as Cangrelor does.

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