NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which oral adjuvant is approved for use in fibromyalgia, PHN, and neuropathic pain?

  1. Pregabalin

  2. Gabapentin

  3. Lamotrigine

  4. Carbamazepine

The correct answer is: Pregabalin

Oral adjuvants are medications used to enhance the effects of other drugs, such as pain medications. Pregabalin, also known as Lyrica, has been approved by the FDA for use in treating fibromyalgia, postherpetic neuralgia (PHN), and neuropathic pain. It works by decreasing abnormal brain activity and helps to control seizures and nerve pain. Gabapentin (choice B) is also used for similar conditions, but it is not specifically approved for fibromyalgia. Lamotrigine (choice C) and carbamazepine (choice D), both anticonvulsant medications, are primarily used for seizures and are not approved for fibromyalgia, PHN, or neuropathic pain.

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