NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which SNRI is indicated only for fibromyalgia?

  1. Duloxetine

  2. Milnacipran

  3. Venlafaxine

  4. Desipramine

The correct answer is: Milnacipran

Milnacipran is the correct answer because it is the only selective serotonin and norepinephrine reuptake inhibitor (SNRI) that is specifically indicated for the treatment of fibromyalgia. Duloxetine is also an SNRI, but it is indicated for various conditions such as depression, anxiety, and diabetic peripheral neuropathic pain. Venlafaxine is another SNRI indicated for major depressive disorder, generalized anxiety disorder, and panic disorder. Desipramine, on the other hand, is a tricyclic antidepressant that is not an SNRI and is not indicated for fibromyalgia.

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